Mendoza is the capital city of Mendoza Province, in Argentina. It is located in the northern-central part of the province, in a region of foothills and high plains, on the eastern side of the Andes. As of the 2001 census [INDEC], Mendoza's population was 110,993. The metropolitan population was 848,660 in 2001, making Greater Mendoza the fourth largest census metropolitan area in the country.

Ruta Nacional 7, the major road running between Buenos Aires and Santiago, runs through Mendoza. The city is a frequent stopover for climbers on their way to Aconcagua (the highest mountain in the Western Hemisphere) and for adventure travelers interested in mountaineering, hiking, horseback riding, rafting, and other sports. In the winter, skiers come to the city for its easy access to the Andes.

Two of the main industries of the Mendoza area are wine making and olive oil production.

Mendoza has several museums, including the Museo Cornelio Moyano, a natural history museum, and the Museo del Área Fundacional (Historical Regional Foundation Museum) on Pedro del Castillo Square. The Museo Nacional del Vino (National Wine Museum), focusing on the history of winemaking in the area, is 17 km southeast of Mendoza in Maipú. The Casa de Fader, a historic house museum, is an 1890 mansion once home to artist Fernando Fader in nearby Mayor Drummond, 14 km south of Mendoza. The mansion is home to many of the artist's paintings.

The Fiesta Nacional de la Vendimia (The National Grape Harvest Festival) occurs in early March each year. Part of the festivities include a beauty pageant, where 17 beauty queens from each department of Mendoza Province compete, and one winner is selected by a panel of about 50 judges. The queen of Mendoza city's department does not compete and acts as host for the other queens.

In 2008 National Geographic listed Mendoza as one of the top 10 historic destinations in the world.